Article
[Vitexicarpin affects proliferation and apoptosis in mutated p53 breast cancer cell].
Zhonghua yi xue za zhi - 16 Mar 2010
Song Yong-chun, Zhang Xi, Lei Guang-yan, Dang Cheng-xue
Abstract excerpt
OBJECTIVE: To elucidate the effect of proliferation and apoptosis induced by vitexicarpin in mutated p53 Hs578T cell line and study the expression of c-Myc, p21 and Bcl-2 protein in Hs578T and wild p53 MCF-7 cell pre-treated with vitexicarpin. METHODS: Cells were treated with various concentrations of vitexicarpin (0, 0.1, 0.2, 0.5, 1.0 micromol/L). MTT assays were used to detect cell proliferation at different...
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