Alterations in Cell Cycle and Induction of Apoptotic Cell Death in Breast Cancer Cells Treated with<i>α</i>-Mangostin Extracted from Mangosteen Pericarp

Abstract excerpt

The development of molecularly targeted drugs has greatly advanced cancer therapy, despite these drugs being associated with some serious problems. Recently, increasing attention has been paid to the anticancer effects of natural products. α-Mangostin, a xanthone isolated from the pericarp of mangosteen fruit, has been shown to induce apoptosis in various cancer cell lines and to exhibit antitumor activity in a...

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