Article
Ablation of Drosophila photoreceptor cells by conditional expression of a toxin gene.
Genes & development - 1 Jun 1991
Kunes S, Steller H
Abstract excerpt
We have used toxin-mediated ablation to study some aspects of visual system development in Drosophila melanogaster. To devise a method that permits the conditional expression of a cellular toxin, we introduced an amber mutation into the diphtheria toxin-A-chain gene. In transgenic animals, this toxin gene can be activated by providing the gene for an amber suppressor tRNA. By coupling this toxin gene to the...
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