Article
Molecular modeling of cytochrome P450 and drug metabolism.
Current drug metabolism - 1 May 2010
Wang Jing-Fang, Chou Kuo-Chen
Abstract excerpt
The cytochrome P450 family is a large and diverse group of hemoproteins that are located in virtually all types of organism, such as bacteria, eukaryotes and even Archaea. These proteins are found throughout the body, however the highest concentrations are associated with liver. As the Human Genome Project completed, there are 57 genes and more than 59 pseudogenes divided among 18 families of CYP genes and 43...
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