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Article

Nexus between epidermolysis bullosa and transcriptional regulation by thyroid hormone in epidermal keratinocytes.

Clinical and translational science - 1 May 2008

Tomic-Canic Marjana, Stojadinovic Olivera, Lee Brian, Walsh Rebecca, Blumenberg Miroslav

Abstract excerpt

Abstract Thyroid hormone, T3, through the interaction of its receptor with the recognition sequences in the DNA, regulates gene expression. This regulation includes the promoter activity of keratin genes. The receptor shares coregulators with other members of the nuclear receptor family, including RXR. Intending to define the transcriptional effects of thyroid hormones in keratinocytes, we used Affymetrix...

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Topics

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Share to Epidermis
Share to Epidermolysis Bullosa

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix

Share to Keratinocytes

Share to Oligonucleotide Array Sequence Analysis

Share to Receptors, Cytoplasmic and Nuclear

Share to RNA, Complementary

Share to Thyroid Hormones

Source

Open in PubMed Open full text

Identifiers

PMID: 20443817
DOI: 10.1111/j.1752-8062.2008.00015.x
PMCID: PMC4973621

Genes

MMP1
MMP14
MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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