Article
Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation.
The American journal of surgical pathology - 1 Jun 2010
Long Kevin B, Butrynski James E, Blank Seth D, Ebrahim Kurt S, Dressel Douglas M, Heinrich Michael C, Corless Christopher L, Hornick Jason L
Abstract excerpt
Gastrointestinal stromal tumors (GISTs), the most common mesenchymal neoplasms of the tubular gastrointestinal tract, usually originate in the wall of the stomach or small intestine. Most GISTs harbor oncogenic mutations in either the KIT or platelet-derived growth factor receptor alpha (PDGFRA) tyrosine kinase receptor genes and show differentiation along the lines of the interstitial cells of Cajal. Rarely,...
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