Article
Single nucleotide polymorphisms of CD244 gene predispose to renal and neuropsychiatric manifestations with systemic lupus erythematosus.
Modern rheumatology - 1 Oct 2010
Ota Yuko, Kawaguchi Yasushi, Takagi Kae, Tochimoto Akiko, Kawamoto Manabu, Katsumata Yasuhiro, Gono Takahisa, Masuda Ikuko, Ikari Katsunori, Momohara Shigeki, Yamanaka Hisashi
Abstract excerpt
The objective of this study was to explore the association of single nucleotide polymorphisms (SNPs) of the CD244 gene with several clinical features of systemic lupus erythematosus (SLE). Two hundred and forty-three patients with SLE and 369 healthy controls were enrolled. Two SNPs (rs6682654 and rs3766379) in the CD244 gene were determined by allelic discrimination using a specific TaqMan probe. Only SNP...
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