Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation of the Drosophila vesicular GABA transporter disrupts visual figure detection.

The Journal of experimental biology - 1 May 2010

Fei Hao, Chow Dawnis M, Chen Audrey, Romero-Calderón Rafael, Ong Wei S, Ackerson Larry C, Maidment Nigel T, Simpson Julie H, Frye Mark A, Krantz David E

Abstract excerpt

The role of gamma amino butyric acid (GABA) release and inhibitory neurotransmission in regulating most behaviors remains unclear. The vesicular GABA transporter (VGAT) is required for the storage of GABA in synaptic vesicles and provides a potentially useful probe for inhibitory circuits. However, specific pharmacologic agents for VGAT are not available, and VGAT knockout mice are embryonically lethal, thus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Ganglia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Movement

Share to Synaptic Vesicles

Share to Transgenes

Share to Visual Perception

Source

Open in PubMed Open full text

Identifiers

PMID: 20435823
DOI: 10.1242/jeb.036053
PMCID: PMC2861964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation of the Drosophila vesicular GABA transporter disrupts visual figure detection.PMID 20435823Read ↗

Vesicular glutamate transport at a central synapse limits the acuity of visual perception in zebrafish.Semantic proximity Read ↗

Inhibitory neuron-specific Cre-dependent red fluorescent labeling using VGAT BAC-based transgenic mouse lines with identified transgene integration sites.Semantic proximity Read ↗

The blu Blur: mutation of a vesicular glutamate transporter reduces the resolution of zebrafish vision.Semantic proximity Read ↗

Transgenic line for the identification of cholinergic release sites in Drosophila melanogaster.Semantic proximity Read ↗

Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorderSemantic proximity Read ↗

Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin.Semantic proximity Read ↗

The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice.Semantic proximity Read ↗

Functionally Complete Excision of Conditional Alleles in the Mouse Suprachiasmatic Nucleus by Vgat-ires-Cre.Semantic proximity Read ↗

Visuomotor control: Drosophila bridges the gap.Semantic proximity Read ↗

A putative vesicular transporter expressed in Drosophila mushroom bodies that mediates sexual behavior may define a neurotransmitter system.Semantic proximity Read ↗

Sidekick 2 directs formation of a retinal circuit that detects differential motion.Semantic proximity Read ↗

Glutamate, GABA and acetylcholine signaling components in the lamina of the Drosophila visual system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.