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Article

Ligand orientation governs conjugation capacity of UDP-glucuronosyltransferase 1A1.

Journal of biochemistry - 1 Jul 2010

Takaoka Yutaka, Ohta Mika, Takeuchi Atsuko, Miura Kenji, Matsuo Masafumi, Sakaeda Toshiyuki, Sugano Aki, Nishio Hisahide

Abstract excerpt

UDP-glucuronosyltransferase 1A1 (UGT1A1) is an endoplasmic reticulum membrane protein that catalyses glucuronidation. Mutant UGT1A1 possesses a different conjugation capacity, and the molecular mechanisms regulating these conjugation reactions are as yet unclear. To elucidate these molecular mech...

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PMID: 20435641
DOI: 10.1093/jb/mvq048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20435641-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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