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Article

The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion

29 Apr 2010

Abstract excerpt

CD248 is a cell surface receptor that specifically identifies fibroblasts and pericytes during development and in association with cancer and inflammation. However, its function is poorly defined and its role in lymphoid organs not studied. Here, we used (4-hydroxy-3-nitrophenyl)acetyl chicken gamma-globulin immunisation and mice lacking CD248 to study whether CD248 modulates popliteal LN (pLN) expansion and...

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PMID: 20432232
DOI: 10.1002/eji.200939877

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