Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aging-Related Gene Expression in Hippocampus Proper Compared with Dentate Gyrus Is Selectively Associated with Metabolic Syndrome Variables in Rhesus Monkeys

28 Apr 2010

Abstract excerpt

Age-dependent metabolic syndrome (MetS) is a well established risk factor for cardiovascular disease, but it also confers major risk for impaired cognition in normal aging or Alzheimer's disease (AD). However, little is known about the specific pathways mediating MetS-brain interactions. Here, we performed the first studies quantitatively linking MetS variables to aging changes in brain genome-wide expression and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Genetics and Neurodevelopmental Disorders
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20427664
DOI: 10.1523/jneurosci.3956-09.2010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aging-Related Gene Expression in Hippocampus Proper Compared with Dentate Gyrus Is Selectively Associated with Metabolic Syndrome Variables in Rhesus MonkeysPMID 20427664Read ↗

Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive ImpairmentSemantic proximity Read ↗

Transitions in metabolic and immune systems from pre-menopause to post-menopause: implications for age-associated neurodegenerative diseasesSemantic proximity Read ↗

Hippocampal and Cognitive Aging across the Lifespan: A Bioenergetic Shift Precedes and Increased Cholesterol Trafficking Parallels Memory ImpairmentSemantic proximity Read ↗

The Inflammaging-Redox-InflammamiR Axis in Metabolic Aging: From Diagnostic Clusters to Integrated Risk Phenotypes.Semantic proximity Read ↗

Dietary Responses of Dementia-Related Genes Encoding Metabolic EnzymesSemantic proximity Read ↗

The expression of insulin signaling and N-methyl-D-aspartate receptor genes in areas of gray matter atrophy is associated with cognitive function in type 2 diabetesSemantic proximity Read ↗

RUNX1 and YY1 modulate neuronal fate and energy metabolism in Alzheimer's diseaseSemantic proximity Read ↗

Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype.Semantic proximity Read ↗

Temporal dysregulation of PPARG-PRKAG2 co-expression in gray matter: Implications for cognitive decline and intervention targets in type 2 diabetesSemantic proximity Read ↗

Relationship of metabolic and endocrine parameters to brain glucose metabolism in older adults: do cognitively-normal older adults have a particular metabolic phenotype?Semantic proximity Read ↗

Associations of metabolic obesity phenotypes with cognitive aging in middle-aged and elderly Chinese adultsSemantic proximity Read ↗

Canagliflozin reprograms the aging hippocampus in genetically diverse UM-HET3 mice and attenuates Alzheimer’s-like pathologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.