Article
Lesion-specific pattern of immunocytochemical distribution of growth-associated protein B-50 (GAP-43) in the cerebellum of Weaver and PCD-mutant mice: lack of B-50 involvement in neuroplasticity of Purkinje cell terminals?
Journal of neuroscience research - 15 Jun 1994
Bäurle J, Oestreicher A B, Gispen W H, Grüsser-Cornehls U
Abstract excerpt
The growth-associated protein B-50 (GAP-43) is thought to play a major role in the development and regeneration of neurons. The participation of B-50 in neuronal plasticity is well documented, especially for monoaminergic systems. However, such an important role for B-50 in GABAergic systems has not been substantiated to date. This study was performed to obtain detailed information about the identity of B-50...
Topics
- Animals
- Cerebellum
- GAP-43 Protein
- Immunoblotting
- Immunohistochemistry
- Membrane Glycoproteins
- Mice
- Mice, Neurologic Mutants
- Mutation
- Nerve Endings