Lesion-specific pattern of immunocytochemical distribution of growth-associated protein B-50 (GAP-43) in the cerebellum of Weaver and PCD-mutant mice: lack of B-50 involvement in neuroplasticity of Purkinje cell terminals?

Abstract excerpt

The growth-associated protein B-50 (GAP-43) is thought to play a major role in the development and regeneration of neurons. The participation of B-50 in neuronal plasticity is well documented, especially for monoaminergic systems. However, such an important role for B-50 in GABAergic systems has not been substantiated to date. This study was performed to obtain detailed information about the identity of B-50...

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