Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutrons

27 Apr 2010

Abstract excerpt

BACKGROUND: A better understanding of the underlying mechanisms of DNA repair after low- and high-LET radiations represents a research priority aimed at improving the outcome of clinical radiotherapy. To date however, our knowledge regarding the importance of DNA DSB repair proteins and mechanisms in the response of human cells to high-LET radiation, is far from being complete. METHODS: We investigated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Mechanisms
Share to Effects of Radiation Exposure
Share to Nuclear Structure and Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20423515
DOI: 10.1186/1748-717x-5-30

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutronsPMID 20423515Read ↗

Beyond the Target: A Review of Radiation-Induced Bystander Effects in Radiobiology and Radiation TherapySemantic proximity Read ↗

[Radiation biology: major advances and perspectives for radiotherapy].Semantic proximity Read ↗

Cellular radiosensitivity: How much better do we understand it?Semantic proximity Read ↗

Combined Radiations: Biological Effects of Mixed Exposures Across the Radiation SpectrumSemantic proximity Read ↗

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatmentSemantic proximity Read ↗

The Radiobiological Effects of Proton Beam Therapy: Impact on DNA Damage and RepairSemantic proximity Read ↗

Zebrafish as a Model System to Screen Radiation ModifiersSemantic proximity Read ↗

Increased Relative Biological Effectiveness of Orthovoltage X-rays Compared to γ-rays in Preclinical IrradiationSemantic proximity Read ↗

Recent Insights into the Biological Action of Heavy-Ion RadiationSemantic proximity Read ↗

Early Increase of Radiation-induced γH2AX Foci in a Human Ku70/80 Knockdown Cell Line Characterized by an Enhanced RadiosensitivitySemantic proximity Read ↗

Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation.Semantic proximity Read ↗

Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End JoiningSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.