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Article

Recent Insights into the Biological Action of Heavy-Ion Radiation

1 Jan 2009

Abstract excerpt

Biological effectiveness varies with the linear energy transfer (LET) of ionizing radiation. During cancer therapy or long-term interplanetary manned explorations, humans are exposed to high-LET energetic heavy ions that inactivate cells more effectively than low-LET photons like X-rays and gamma-rays. Recent biological studies have illustrated that heavy ions overcome tumor radioresistance caused by Bcl-2...

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PMID: 18838844
DOI: 10.1269/jrr.08070

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