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Article

Searching for footprints of positive selection in whole-genome SNP data from nonequilibrium populations.

Genetics - 1 Jul 2010

Pavlidis Pavlos, Jensen Jeffrey D, Stephan Wolfgang

Abstract excerpt

A major goal of population genomics is to reconstruct the history of natural populations and to infer the neutral and selective scenarios that can explain the present-day polymorphism patterns. However, the separation between neutral and selective hypotheses has proven hard, mainly because both may predict similar patterns in the genome. This study focuses on the development of methods that can be used to...

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Identifiers

PMID: 20407129
DOI: 10.1534/genetics.110.116459
PMCID: PMC2907208

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