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Article

Statistical tests for detecting positive selection by utilizing high-frequency variants.

Genetics - 1 Nov 2006

Zeng Kai, Fu Yun-Xin, Shi Suhua, Wu Chung-I

Abstract excerpt

By comparing the low-, intermediate-, and high-frequency parts of the frequency spectrum, we gain information on the evolutionary forces that influence the pattern of polymorphism in population samples. We emphasize the high-frequency variants on which positive selection and negative (background) selection exhibit different effects. We propose a new estimator of theta (the product of effective population size and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16951063
DOI: 10.1534/genetics.106.061432
PMCID: PMC1667063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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