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Article

Isolation and characterization of extragenic suppressor mutants of the tolA-876 periplasmic-leaky allele in Escherichia coli K-12.

FEMS microbiology letters - 1 Mar 1991

Amouroux C, Lazzaroni J C, Portalier R

Abstract excerpt

tolA mutants of Escherichia coli K-12 release periplasmic proteins into the extracellular medium; they are sensitive to growth inhibitors such as cholic acid and tolerant to group A colicins and filamentous bacteriophage. Suppressor mutants of the tolA-876 allele were isolated by selecting for cholic acid resistant clones that did not release periplasmic ribonuclease I. One class of tolA suppressor strains...

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PMID: 2040438
DOI: 10.1016/0378-1097(91)90176-b

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