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Article

Isolation and characterization of extragenic suppressor mutants of the tolA-876 periplasmic-leaky allele in Escherichia coli K-12.

FEMS microbiology letters - 1 Mar 1991

Amouroux C, Lazzaroni J C, Portalier R

Abstract excerpt

tolA mutants of Escherichia coli K-12 release periplasmic proteins into the extracellular medium; they are sensitive to growth inhibitors such as cholic acid and tolerant to group A colicins and filamentous bacteriophage. Suppressor mutants of the tolA-876 allele were isolated by selecting for cholic acid resistant clones that did not release periplasmic ribonuclease I. One class of tolA suppressor strains...

Topics

Alkaline Phosphatase
Alleles
Bacterial Outer Membrane Proteins
Cell Fractionation
Cell Membrane
Chromosome Mapping
Colicins
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Mutation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Suppression, Genetic

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PMID: 2040438
DOI: 10.1016/0378-1097(91)90176-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2040438-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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