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Article

Improved KIR gene and HLA-C KIR ligand sequence-specific primer polymerase chain reaction genotyping using whole genome amplification.

Tissue antigens - 1 Aug 2010

Chainonthee W, Böttcher G, Gagne K, Füssel M, Bignon J-D, Wassmuth R

Abstract excerpt

Molecular analysis of genetic polymorphism for clinical or research purposes may be compromised by genomic DNA of limited quality and quantity. In this study, we have successfully tested the feasibility of using whole genome amplification (WGA) to allow genotyping for killer cell immunoglobulin-like receptor (KIR) genes and human leucocyte antigen (HLA)-C KIR ligand dimorphism on HLA-C. WGA was achieved by...

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Identifiers

PMID: 20403144
DOI: 10.1111/j.1399-0039.2010.01479.x

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