Article
DD genotype of the angiotensin-converting enzyme gene and stroke in Slovenian population.
Pflugers Archiv : European journal of physiology - 1 Jan 2000
Peterlin B, Milanez T, Kobal J, Peterlin-Potisk K, Petrovic D, Grad A, Pogacnik T
Abstract excerpt
The angiotensin-converting enzyme (ACE) is a rate-limiting enzyme in the renin angiotensin system, the enzyme is involved in the vascular remodelling and atherosclerosis. Its significance in pathogenesis of ischemic cerebrovascular insults (CVI) is not known. We analysed 124 Slovenian patients with CVI and compared them with 161 healthy controls for I/D polymorphism. Under a recessive model (chi2 = 1.76, p = 0.1,...
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