Article
Susceptibility to N-methyl-D-aspartate toxicity in morphological and functional types of cat retinal ganglion cells.
Japanese journal of ophthalmology - 1 Mar 2010
Nakazawa Toru, Watanabe Masami, Kudo Hideyo, Nishida Kohji, Tamai Makoto
Abstract excerpt
BACKGROUND: To examine whether different types of retinal ganglion cells (RGCs) in the cat retina have different survival rates when exposed to N-methyl-D-aspartate (NMDA). METHODS: NMDA injury was induced by intravitreal administration of NMDA at final concentrations of 0.2, 0.4, 0.6, and 0.8 mM. The total number of surviving RGCs and their distribution were counted by retrograde labeling with a fluorescent dye....
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