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Article

Replication of genetic association studies in asthma and related phenotypes.

Journal of human genetics - 1 Jun 2010

Undarmaa Siizkhuu, Mashimo Yoichi, Hattori Satoshi, Shimojo Naoki, Fujita Kimie, Miyatake Akihiko, Doi Satoru, Kohno Yoichi, Okamoto Yoshitaka, Hirota Tomomitsu, Tamari Mayumi, Hata Akira, Suzuki Yoichi

Abstract excerpt

In asthma genetics, the association of highly replicated susceptibility genes lacks consistency across populations. To identify genuine associations, we investigated the reproducibility of the 23 most promising asthma and asthma-related candidate genes in a moderately sized sample from the Japanese population. We compared the frequency of 33 polymorphisms in unrelated cases and controls and tested for their...

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Source

Identifiers

PMID: 20395963
DOI: 10.1038/jhg.2010.32

Genes

ADAM33
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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