Article
Association of IL-4 and ADAM33 gene polymorphisms with asthma in an Indian population.
Lung - 1 Oct 2010
Bijanzadeh Mahdi, Ramachandra Nallur B, Mahesh P A, Mysore R Savitha, Kumar Pradeep, Manjunath B S, Jayaraj B S
Abstract excerpt
There are more than 100 candidate genes of asthma located on 23 human chromosomes. Interleukin-4 (IL-4), located on chromosome 5q31, and ADAM33, located on chromosome 20p13, and some single nucleotide polymorphisms (SNPs) of these genes have been shown to be associated with asthma and its manifestations in different populations. The most prominent SNPs of IL-4 and ADAM33 are 589C>T and 400A>G, respectively. There...
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