Article
Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma.
Cancer research - 15 Apr 2010
Woo Hyun Goo, Lee Jeong-Hoon, Yoon Jung-Hwan, Kim Chung Yong, Lee Hyo-Suk, Jang Ja June, Yi Nam-Joon, Suh Kyung-Suk, Lee Kuhn Uk, Park Eun Sung, Thorgeirsson Snorri S, Kim Yoon Jun
Abstract excerpt
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the major adult liver cancers. The existence of combined hepatocellular-cholangiocarcinoma (CHC), a histopathologic intermediate form between HCC and CC, suggests phenotypic overlap between these tumors. Here, we applied an integrative oncogenomic approach to address the clinical and functional implications of the overlapping phenotype between these...
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