Article
Genetic polymorphisms of glutathione S-transferase genes GSTP1, GSTM1, and GSTT1 and risk of esophageal and gastric cardia cancers.
Cancer causes & control : CCC - 1 Dec 2009
Zendehdel Kazem, Bahmanyar Shahram, McCarthy Shane, Nyren Olof, Andersson Bjorn, Ye Weimin
Abstract excerpt
Glutathione S-transferase (GST) enzymes are known to metabolize tobacco-related carcinogens. Previous studies on the association of functional polymorphisms of GST genes with esophageal squamous cell carcinoma have yielded conflicting but overall null results. A few studies of esophageal adenocarcinoma were likewise conflicting, but the scarcity of data is striking. We aimed to study associations of the GSTM1 and...
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