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Article

Mutational analysis of calnexin.

Biochimica et biophysica acta - 1 Jun 2011

Groenendyk Jody, Dabrowska Monika, Michalak Marek

Abstract excerpt

Calnexin is a type I endoplasmic reticulum lectin-like chaperone protein. In this study, we have used site-specific mutagenesis to investigate the functional importance of glutamate E351 found at the tip of the P-domain of calnexin, and tryptophan W428 found in the carbohydrate binding region of the globular domain of the protein. The E351 and W428 calnexin mutants lost the ability to inhibit aggregation of IgY...

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Identifiers

PMID: 20385098
DOI: 10.1016/j.bbamem.2010.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of calnexin.PMID 20385098Read ↗

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