Article
Imperfect oligodendrocytic and neuronal differentiation of glioblastoma cells.
Folia neuropathologica - 1 Jan 2010
Wolańczyk Magdalena, Hułas-Bigoszewska Krystyna, Witusik-Perkowska Monika, Papierz Wielisław, Jaskólski Dariusz, Liberski Paweł P, Rieske Piotr
Abstract excerpt
Previously, we have reported that glioblastoma (GBM) cells can be differentiated into cells showing neuronal, glial and non-neural (mesenchymal) phenotypes. Before the differentiation the GBM cells co-expressed GFAP, CD44, Beta III tubulin, MAP2, Vimentin, Nestin and SOX-2, whereas during the exposure to a neural differentiation medium the differentiation process was arrested at the early stages and the GBM cells...
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