Article
FAM5C contributes to aggressive periodontitis.
PloS one - 7 Apr 2010
Carvalho Flavia M, Tinoco Eduardo M B, Deeley Kathleen, Duarte Poliana M, Faveri Marcelo, Marques Marcelo R, Mendonça Adriana C, Wang Xiaojing, Cuenco Karen, Menezes Renato, Garlet Gustavo P, Vieira Alexandre R
Abstract excerpt
Aggressive periodontitis is characterized by a rapid and severe periodontal destruction in young systemically healthy subjects. A greater prevalence is reported in Africans and African descendent groups than in Caucasians and Hispanics. We first fine mapped the interval 1q24.2 to 1q31.3 suggested as containing an aggressive periodontitis locus. Three hundred and eighty-nine subjects from 55 pedigrees were...
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