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Article

The influence of selenium and selenoprotein gene variants on colorectal cancer risk.

Mutagenesis - 1 Mar 2012

Méplan Catherine, Hesketh John

Abstract excerpt

Colorectal cancer (CRC) is a major cause of mortality throughout the world and risk of CRC is known to be modulated by nutritional factors. Low intake of the micronutrient selenium (Se) has been implicated as a risk factor in CRC, and in this article we describe the biochemical functions of selenium in selenoproteins, review the evidence for an association of selenium status with CRC and adenoma risk and describe...

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Identifiers

PMID: 22294765
DOI: 10.1093/mutage/ger058

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