Article
Four-Generation Pedigree of Monozygotic Female Twins Reveals Genetic Factors in Twinning Process by Whole-Genome Sequencing.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Oct 2018
Liu Shiqi, Hong Yaqiang, Cui Kai, Guan Jinxia, Han Lu, Chen Wei, Xu Zhe, Gong Kenan, Ou Yang, Zeng Changqing, Li Sheng, Zhang Dake, Hu Dawei
Abstract excerpt
Familial monozygotic (MZ) twinning reports are rare around the world, and we report a four-generation pedigree with seven recorded pairs of female MZ twins. Whole-genome sequencing of seven family members was performed to explore the featured genetic factors in MZ twins. For variations specific to MZ twins, five novel variants were observed in the X chromosome. These candidates were used to explain the seemingly...
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