Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebrospinal fluid promotes survival and astroglial differentiation of adult human neural progenitor cells but inhibits proliferation and neuronal differentiation

8 Apr 2010

Abstract excerpt

BACKGROUND: Neural stem cells (NSCs) are a promising source for cell replacement therapies for neurological diseases. Growing evidence suggests an important role of cerebrospinal fluid (CSF) not only on neuroectodermal cells during brain development but also on the survival, proliferation and fate specification of NSCs in the adult brain. Existing in vitro studies focused on embryonic cell lines and embryonic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebrospinal fluid and hydrocephalus
Share to Mesenchymal stem cell research
Share to Neurogenesis and neuroplasticity mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20377845
DOI: 10.1186/1471-2202-11-48

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebrospinal fluid promotes survival and astroglial differentiation of adult human neural progenitor cells but inhibits proliferation and neuronal differentiationPMID 20377845Read ↗

Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cellsSemantic proximity Read ↗

Neural Stem Cells, Neural Progenitors, and Neurotrophic FactorsSemantic proximity Read ↗

Diversity of Adult Neural Stem and Progenitor Cells in Physiology and DiseaseSemantic proximity Read ↗

Pediatric glioblastoma cells inhibit neurogenesis and promote astrogenesis, phenotypic transformation and migration of human neural progenitor cells within cocultures.Semantic proximity Read ↗

Adult hippocampal neural stem and progenitor cells regulate the neurogenic niche by secreting VEGF.Semantic proximity Read ↗

Adherent Neural Stem (NS) Cells from Fetal and Adult ForebrainSemantic proximity Read ↗

Concise Review: Adult Mesenchymal Stem Cells, Adult Neural Crest Stem Cells, and Therapy of Neurological Pathologies: A State of PlaySemantic proximity Read ↗

Adult Human Brain Neural Progenitor Cells (NPCs) and Fibroblast-Like Cells Have Similar Properties In Vitro but Only NPCs Differentiate into NeuronsSemantic proximity Read ↗

Neural Stem Cells and Fetal-Onset HydrocephalusSemantic proximity Read ↗

Epigenetic conversion of human adult bone mesodermal stromal cells into neuroectodermal cell types for replacement therapy of neurodegenerative disordersSemantic proximity Read ↗

Human neural stem cells: isolation, expansion and transplantation.Semantic proximity Read ↗

Heparan Sulfate Proteoglycans Mediate In Vitro Human Neuronal Lineage SpecificationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.