Article
Lessons from Lynch syndrome: a tumor biology-based approach to familial colorectal cancer.
Future oncology (London, England) - 1 Apr 2010
Buchanan Daniel D, Roberts Aedan, Walsh Michael D, Parry Susan, Young Joanne P
Abstract excerpt
Colorectal cancer (CRC) develops within precursor lesions in the single-celled epithelial lining of the gut. The two most common epithelial lesions are the adenoma and the serrated polyp. CRC is also one of the most familial of the common cancers, and just as there are syndromes associated with increased risk of CRC arising in adenomas, there are also syndromes with increased CRC risk associated with serrated...
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