Article
Linkage and association study of discoidin domain receptor 1 as a novel susceptibility gene for childhood IgA nephropathy.
International journal of molecular medicine - 1 May 2010
Hahn Won-Ho, Suh Jin-Soon, Cho Byoung-Soo, Kim Sung-Do
Abstract excerpt
In several experimental studies, it has been suggested that discoidin domain receptor 1 (DDR1) plays an important role in the regulation of mesangial proliferation, glomerular basement membrane thickening, renal fibrosis, and in the development of inflammation in several tissue types, including renal tissues. The present study was conducted to investigate the association between single nucleotide polymorphisms...
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