Article
Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing.
Journal of receptor and signal transduction research - 1 Jun 2010
Okajima Daisuke, Kudo Gen, Yokota Hiroshi
Abstract excerpt
Brain-specific angiogenesis inhibitor 2 (BAI2) is a member of adhesion-G protein-coupled receptors (GPCRs). BAI2 is dominantly expressed in the brain and its physiological ligands and functions are still unclear. Adhesion-GPCRs, including BAI2, commonly have a long N-terminal extracellular region (ECR) containing the GPCR proteolysis site (GPS) and the cleavage of the ECR at the GPS domain is suspected to be...
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