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Article

Mutation landscapes.

Journal of theoretical biology - 21 Sept 2003

Sasaki Akira, Nowak Martin A

Abstract excerpt

A traditional picture of evolutionary dynamics with constant fitness is that of genomes living in sequence space and adapting on fitness landscapes. Mutation rates are considered to be constant or externally regulated. If, however, we take into account that genomes also encode for enzymes that perform replication and error correction, then individual genomes not only have a specific replication rate (fitness),...

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PMID: 12927530
DOI: 10.1016/s0022-5193(03)00161-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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