Evolution in the weak-mutation limit: Stasis periods punctuated by fast transitions between saddle points on the fitness landscape.

Abstract excerpt

A mathematical analysis of the evolution of a large population under the weak-mutation limit shows that such a population would spend most of the time in stasis in the vicinity of saddle points on the fitness landscape. The periods of stasis are punctuated by fast transitions, in lnNe/s time (Ne , effective population size; s, selection coefficient of a mutation), when a new beneficial mutation is fixed in the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Evolution, Molecular
• Share to Genetics, Population