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Article

IL-4R{alpha}-responsive smooth muscle cells increase intestinal hypercontractility and contribute to resistance during acute Schistosomiasis.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jun 2010

Marillier Reece G, Brombacher Tiroyaone M, Dewals Benjamin, Leeto Mosiuoa, Barkhuizen Mark, Govender Dhirendra, Kellaway Lauriston, Horsnell William G C, Brombacher Frank

Abstract excerpt

Interleukin-(IL)-4 and IL-13 signal through heterodimeric receptors containing a common IL-4 receptor-alpha (IL-4Ralpha) subunit, which is important for protection against helminth infections, including schistosomiasis. Previous studies demonstrated important roles for IL-4Ralpha-responsive hematopoietic cells, including T cells and macrophages in schistosomiasis. In this study, we examined the role of IL-4Ralpha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20360135
DOI: 10.1152/ajpgi.00321.2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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