Article
Antibodies and immune effectors: shaping Gram-negative bacterial phenotypes.
Trends in microbiology - 1 Jun 2010
Wade William F, O'Toole George A
Abstract excerpt
Antibodies and immune effectors (IE) are crucial for protecting humans from Gram-negative bacteria. Antibodies can bind outer membrane or cell surface (e.g. flagella) structures, thereby preventing adhesion, disrupting specific virulence functions, or targeting bacteria for phagocytosis. IE (antimicrobial peptides, cytokines and hormones) impinge on bacterial infections and regulate immune responses. A developing...
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