Article
Effect of cetuximab treatment in squamous cell carcinomas.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2010
Nestor Marika
Abstract excerpt
The purpose of this study was to assess the effects of the monoclonal antibody cetuximab in a panel of cultured squamous cell carcinoma cell lines. This antibody, targeting the epidermal growth factor receptor (EGFR), is emerging as a promising agent for treatment of several cancers. As this antibody comes into clinical use, the identification of predictive markers of therapeutic benefit remains a pressing issue....
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