Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice

31 Mar 2010

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Hormonal Regulation and Hypertension
Share to Pharmacogenetics and Drug Metabolism

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20354104
DOI: 10.1124/dmd.109.031872

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in MicePMID 20354104Read ↗

Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female miceSemantic proximity Read ↗

A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A inductionSemantic proximity Read ↗

Identification of mineralocorticoid and glucocorticoid receptors on peripheral nociceptors: Translation of experimental findings from animal to human biologySemantic proximity Read ↗

Dexamethasone and sex regulate placental glucocorticoid receptor isoforms in miceSemantic proximity Read ↗

A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response.Semantic proximity Read ↗

Exploring the role of sex steroids through studies of receptor deficient miceSemantic proximity Read ↗

Construction and characterization of a reporter gene cell line for assessment of human glucocorticoid receptor activationSemantic proximity Read ↗

Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoter.Semantic proximity Read ↗

The Pregnane X Receptor Gene-Humanized Mouse: A Model for Investigating Drug-Drug Interactions Mediated by Cytochromes P450 3ASemantic proximity Read ↗

Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.Semantic proximity Read ↗

PXR-mediated induction of human CYP3A4 and mouse Cyp3a11 by the glucocorticoid budesonideSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.