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Role of Genetic Polymorphism and Expression of Angiopoietin-2 in Patients with Primary Liver Cancer Among the Southeastern Chinese Hans Population.

Genetic testing and molecular biomarkers - 1 Jun 2023

Wang Bin, Lv Yunxiao, Ye Shenjian, Zhao Jin, Pan Xinling

Abstract excerpt

Background: Angiopoietin-2 (Ang2)-mediated angiogenesis plays a crucial role in the pathogenesis of vascular-rich cancers. However, the genetic polymorphism and expression level of Ang2 in patients with primary liver cancer remain unknown. Methods: This study included 234 primary liver cancer patients and 199 healthy controls. The expression levels of Ang2 in liver cancer tissues and plasma were determined....

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PMID: 37382908
DOI: 10.1089/gtmb.2022.0198

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