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Article

CobB regulates Escherichia coli chemotaxis by deacetylating the response regulator CheY.

Molecular microbiology - 1 Jun 2010

Li Ru, Gu Jing, Chen Yuan-Yuan, Xiao Chuan-Le, Wang Li-Wei, Zhang Zhi-Ping, Bi Li-Jun, Wei Hong-Ping, Wang Xu-De, Deng Jiao-Yu, Zhang Xian-En

Abstract excerpt

The silent information regulator (Sir2) family proteins are NAD+-dependent deacetylases. Although a few substrates have been identified, functions of the bacteria Sir2-like protein (CobB) still remain unclear. Here the role of CobB on Escherichia coli chemotaxis was investigated. We used Western blotting and mass spectrometry to show that the response regulator CheY is a substrate of CobB. Surface plasmon...

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Identifiers

PMID: 20345663
DOI: 10.1111/j.1365-2958.2010.07125.x
PMCID: PMC2883070

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SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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CobB regulates Escherichia coli chemotaxis by deacetylating the response regulator CheY.PMID 20345663Read ↗

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Investigation of the role of electrostatic charge in activation of the Escherichia coli response regulator CheY.Semantic proximity Read ↗

Synthesis and biochemical characterization of a phosphorylated analogue of the response regulator CheB.Semantic proximity Read ↗

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