Article
Novel mutations in the respiratory syncytial virus G gene identified in viral isolates from a girl with severe combined immune deficiency treated with intravenous immune globulin.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2006
Lazar Isaac, Canaan Allon, Weibel Carla, Kahn Jeffrey S
Abstract excerpt
BACKGROUND: Respiratory syncytial virus (RSV) can cause prolonged infections in individuals with compromised immunity. OBJECTIVES: To investigate whether RSV evolves during prolonged infection in an immunocompromised host. STUDY DESIGN: We sequenced the envalope glycoprotein genes of RSV obtained at three time points during a 59-day period from a 4-year-old female with severe combined immune deficiency (SCID)...
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