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Genetic analysis and antigenic characterization of human respiratory syncytial virus group A viruses isolated in Germany 1996-2008.

Virus genes - 1 Oct 2013

Adams Ortwin, Werzmirzowsky Judith, Hengel Hartmut

Abstract excerpt

The genetic and antigenic variability of 18 human respiratory syncytial virus group A viruses isolated in Germany from 1996 to 2008 was evaluated by nucleotide sequencing of the complete G and F genes and enzyme-linked immunosorbent assay analysis with anti-G and anti-F monoclonal antibodies. Phylogenetic analyses showed that the G-proteins clustered into the two genotypes GA2 and GA5. The antigenic analysis of...

Topics

Amino Acid Substitution
Antibodies, Viral
Antigens, Viral
Genetic Variation
Germany
Humans
Molecular Sequence Data
Mutant Proteins
RNA, Viral
Respiratory Syncytial Virus Infections
Respiratory Syncytial Virus, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Viral Fusion Proteins

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PMID: 23775758
DOI: 10.1007/s11262-013-0936-9

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