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Article

Optimization of anticoagulation with warfarin for stroke prevention: pharmacogenetic considerations.

American journal of therapeutics - 1 May 2011

Tomek Ales, Matoska Vaclav, Eisert Christian, Serebruany Victor L

Abstract excerpt

Warfarin is a cornerstone of oral anticoagulation for stroke prevention. Anticoagulation with warfarin in patients with atrial fibrillation is over twice as effective in secondary prevention of stroke as any other tested alternatives, including all other antithrombotic drugs or surgical interventions. General belief is that warfarin is capable of preventing 20 ischemic strokes for every hemorrhagic one it causes....

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Source

Identifiers

PMID: 20335792
DOI: 10.1097/MJT.0b013e3181cea0cd

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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