Article
Association of MAOA, 5-HTT, and NET promoter polymorphisms with gene expression and protein activity in human placentas.
Physiological genomics - 1 Jun 2010
Zhang Huiping, Smith Graeme N, Liu Xudong, Holden Jeanette J A
Abstract excerpt
Monoamine oxidase A (MAOA) and the transporters for serotonin (5-HTT) and norepinephrine (NET) may play important roles in regulating maternal monoamine neurotransmitters transferred across the placenta to the fetus. We investigated whether promoter polymorphisms in MAOA (uVNTR), 5-HTT (5-HTTLPR), and NET (NETpPR AAGG(4)) could influence gene expression and protein activity in human placentas. Normal term human...
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