Article
Bagging optimal ROC curve method for predictive genetic tests, with an application for rheumatoid arthritis.
Journal of biopharmaceutical statistics - 1 Mar 2010
Lu Qing, Cui Yuehua, Ye Chengyin, Wei Changshuai, Elston Robert C
Abstract excerpt
Translation studies have been initiated to assess the combined effect of genetic loci from recently accomplished genome-wide association studies and the existing risk factors for early disease prediction. We propose a bagging optimal receiver operating characteristic (ROC) curve method to facilitate this research. Through simulation and real data application, we compared the new method with the commonly used...
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