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Article

A non-parametric method for building predictive genetic tests on high-dimensional data.

Human heredity - 1 Jan 2011

Ye Chengyin, Cui Yuehua, Wei Changshuai, Elston Robert C, Zhu Jun, Lu Qing

Abstract excerpt

OBJECTIVE: Predictive tests that capitalize on emerging genetic findings hold great promise for enhanced personalized healthcare. With the emergence of a large amount of data from genome-wide association studies (GWAS), interest has shifted towards high-dimensional risk prediction. METHODS: To form predictive genetic tests on high-dimensional data, we propose a non-parametric method, called the 'forward ROC...

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PMID: 21778735
DOI: 10.1159/000327299

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PTPN22

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