Article
Association analysis of 33 lipoprotein candidate genes in multi-generational families of African ancestry.
Journal of lipid research - 1 Jul 2010
Miljkovic I, Yerges-Armstrong L M, Kuller L H, Kuipers A L, Wang X, Kammerer C M, Nestlerode C S, Bunker C H, Patrick A L, Wheeler V W, Evans R W, Zmuda J M
Abstract excerpt
African ancestry individuals have a more favorable lipoprotein profile than Caucasians, although the mechanisms for these differences remain unclear. We measured fasting serum lipoproteins and genotyped 768 tagging or potentially functional single nucleotide polymorphisms (SNPs) across 33 candidate gene regions in 401 Afro-Caribbeans older than 18 years belonging to 7 multi-generational pedigrees (mean family...
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