Article
Response of cholesterol synthesis to cholesterol feeding in men with different apolipoprotein E genotypes.
Metabolism: clinical and experimental - 1 Aug 1993
Jones P J, Main B F, Frohlich J J
Abstract excerpt
To investigate the influence of dietary cholesterol level and apolipoprotein (apo) E polymorphism on cholesterol synthesis, seven apo E2/- and six apo E4/- normolipidemic subjects consumed self-selected diets containing low cholesterol ([LC] 250 mg/d) and high cholesterol ([HC] 800 mg/d) levels for approximately 20 days. On day 20, subjects were given 0.7 g deuterium oxide (D2O)/kg body water followed by...
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