Correlation of response of aplastic anemia patients to antilymphocyte globulin with in vitro lymphocyte stimulatory effect: predictive value of in vitro test for clinical response.

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Article

Correlation of response of aplastic anemia patients to antilymphocyte globulin with in vitro lymphocyte stimulatory effect: predictive value of in vitro test for clinical response.

Blood - 15 May 1991

Abe T, Matsuoka H, Kojima S, Kamachi Y, Tsuge I, Kodera Y, Matsuyama T

Abstract excerpt

Therapy with antilymphocyte globulin (ALG) has been shown to be effective in restoring hematopoiesis to some patients with aplastic anemia. It would be useful to have a method for predicting those likely to be responders versus nonresponders. The mode of immunostimulatory action of ALG is of interest in addition to its immunosuppressive action. We examined in vitro the distribution of the proliferative responses...

Topics

Adolescent
Adult
Anemia, Aplastic
Antilymphocyte Serum
Cell Division
Cells, Cultured
Child
Child, Preschool
Dose-Response Relationship, Drug
Female
Flow Cytometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Granulocyte-Macrophage Colony-Stimulating Factor

Hematopoiesis

Humans

Lymphocyte Activation

Male

Monocytes

Phenotype

Source

Open in PubMed

Identifiers

PMID: 2029581

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2029581-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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